What is Doctor’s Best Proteolytic Enzymes? Doctor’s Best Proteolytic Enzymes provides a broad spectrum of vegetarian proteolytic enzymes that provide support for muscle, joint, and overall tissue health. Proteolytic enzymes aid the body in digestion and convert proteins into their constituent amino acids. Enzymes are required to facilitate many diverse chemical reactions in the body. Supplementing with proteolytic enzymes augments many metabolic functions performed by endogenously produced enzymes. How does it work? Doctor’s Best Proteolytic Enzymes is a broad spectrum high-quality proteolytic enzyme formula which includes a variety of plant, bacterial, and fungal proteases. The goal was to create a blend that works at a variety of pH levels to support the body’s enzymatic needs. Maintaining optimal enzymatic function is a key factor in supporting health and wellness. Proteases - types of enzymes whose catalytic function is to hydrolyze (break) protein linkages. Proteases differ in their ability to hydrolyze various peptide bonds. Bacterial proteases are generally optimally active in alkaline conditions, fungal proteases in more acidic conditions, and neutral proteases (from bacteria) are active at a neutral pHs. Bromelain - is a family of proteolytic enzymes derived from the pineapple plant. Bromelain has a variety of physiological mechanisms through which it exerts its effects. Papain - a proteolytic enzyme derived from the unripe papaya. Traditionally used in combination with bromelain. Serratiopeptidase - This proteolytic enzyme has been shown to be more powerful than the proteolytic enzymes produced in the pancreas, chymotrypsin and trypsin. Fungal amylase - an enzyme derived from the fungus Aspergillus oryza. Breaks down carbohydrates, such as starch, and glycogen. Lipase - the main enzyme responsible for breaking down fats. Lipases hydrolyze triglycerides (fats) into their component fatty acid and glycerol molecules.