Facts derived from Ayurveda texts and modern research: Karela contains constituents that act like insulin to help manage blood sugar. The herb helps maintain healthy glucose levels by supporting restoration of functional pancreatic beta cells that secrete insulin in the body. Karela promotes the body tissues to make healthy use of glucose by overcoming insulin resistance The herb has antioxidant properties that reduce the risk of glucose instability complications by helping scavenge cell-damaging effects of free radicals.