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Recent research has shown that a tannin-rich extract derived from the edible fruit of the Terminalia bellerica tree helps keep uric acid levels within healthy range. This patent-pending, standardized extract from Terminalia bellerica inhibits xanthine oxidase, thus modulating uric acid synthesis. The bioactive compounds in Terminalia bellerica are also believed to provide a healthy inflammatory response, possibly due to inhibition of inducible nitric oxide synthase (iNOS). In a 24-week active-control trial, volunteers with elevated uric acid levels who received twice-daily capsules of 500 mg of T. bellerica extract demonstrated decreased uric acid levels by a mean of 27.59%, with no reported adverse side effects. This decrease in uric acid levels enabled 88.8% of the people in the study arm who were taking the extract to achieve targeted uric acid serum levels.
