What is Doctor’s Best Pure L-Ornithine? Doctor’s Best Pure L-Ornithine is an amino acid that helps in the formation of citrulline, proline, and glutamic acid, three amino acids that help supply energy to every cell in the body. L-Ornithine helps support athletic performance and helps lower exercise-induced fatigue, especially when combined with other amino acids. Doctor’s Best L-Ornithine powder is unflavored and can be combined with water, protein-shakes, or your favorite sports performance drink.