Supports Nitric Oxide Production, Exercise Recovery and Liver Detoxification. The amino acid L-Citrulline is a substrate in the cycle that includes L-arginine and L-ornithine. L-Citrulline supports nitric oxide production, which is important for blood pressure regulation, immune function, healing, as well as helping the liver detoxify ammonia. Quatrefolic (Methyl Folate) is the 4th generation of methyl folate and can cross the blood-brain barrier. Methyl Folate is needed to support cardiovascular and neurological health as well as proper cell division. Folate and Gamma Tocopherol work with L-Citrulline to support the production of nitric oxide.