Yamamoto Nutrition Insulomin-R is a food supplement providing plant extracts (berberis, bitter melon, gymnema, Chinese cinnamon), with chromium and R-alpha-lipoic acid. Chromium contributes to the maintenance of normal blood glucose levels and to regular macronutrient metabolism. Moreover, gymnema extract supports appetite control. Insulomin-R is enhanced with R-alpha-lipoic acid. We re well aware nowadays that over prolonged periods of time, diets with excessive amounts of carbohydrates decrease insulin sensitivity, leading to a loss of the effective use of carbohydrates ingested, and a progressive tendency not only to the accumulate fat, but also towards more significant systemic inflammation. Furthermore, the relationship between insulin levels and a cell s sensitivity to its action is unclear. Continuous levels of hyper insulinaemia can, over time, cause alterations in the effective use of carbohydrates, and in their metabolism by muscle cells, with a down regulation of expression of the fat oxidation gene. The more powerful the insulin response is, the more resistant muscle cells in particular will become to its effects, causing an excess of the unused circulating glucose being converted into triglycerides via de novo lipogenesis. These triglycerides then go to construct storage material in adipose tissue and feed an altered metabolic situation that runs contrary to the objectives of any athlete, in terms of muscle building, weight loss, and health in general. Therefore, the fundamental objective for any athlete who wants to maintain proper nutrients partitioning, i.e. an efficient distribution of nutrients, in muscle cells in particular, is to take action to maintain a high insulin sensitivity, primarily through training and dietary interventions, but also with the support of effective supplements, such as the so-called Glucose Disposal Agents. These GDAs are dietary supplements that help the body absorb carbohydrates more efficiently and direct them towards the formation of muscle and liver glycogen. They support the work and intensity of insulin itself, improving muscle cell sensitivity, and encouraging the ingested carbohydrates to convert into new muscle glycogen, thereby optimising training performance and promoting muscle recovery. They not only help stabilise blood glucose levels and promote the release of insulin, but also act as an actual vehicle, which attempts to open the doors on muscle cells to carbohydrates, as well as promoting recovery processes and thermogenesis. INSULOMIN-R is the most innovative and complete of these, but above all it s the most effective Glucose Disposal Agent we can find, and thanks