Important Joint Lubricant With MSM Hyaluronic Acid is a compound present in every tissue of the body, with the highest concentrations occurring in connective tissues such as skin and cartilage. Hyaluronic Acid is an important constituent of joint fluid, where it serves as a lubricant and plays a role in resisting compressive forces. MSM was added to this product as a natural sulfur compound, offering the chemical links needed to form and maintain connective tissues in the human body including articular cartilage.