What is Doctor’s Best 3000 GDU Bromelain? Bromelain is an enzyme derived from pineapple stem and fruit that has proteolytic (protein-digesting) properties. The bromelain found in Doctor’s Best 3000 GDU Bromelain is a potent form of this enzyme. The 3000 GDU refers to the standardization of enzymatic potency and reflects the quality of the raw material used in the product. Bromelain is renowned for its digestion-enhancing characteristics and also has beneficial systemic effects within the body. How does it work? Bromelain has the ability to activate various immune cells and their cytokines. Cytokines are signaling molecules secreted by immune cells that act as messengers to alert other immune cells. In vitro trials have shown that bromelain can alter immune cell secretion of cytokines in a way that would be favorable for maintaining balance in the human immune system. There is also in vitro evidence that bromelain can alter T cell signal transduction, facilitating immune cell communication, which would also contribute to a balanced immune response in the human body. Bromelain’s enzymatic activity is key in these reactions, and Best 3000 GDU Bromelain offers this high potency solution. Evidence suggests that bromelain can modulate adhesion molecules on blood cells and the cells lining the walls of blood vessels, thereby promoting healthy circulation. Bromelain does so through its proteolytic activity of cleaving proteins from the surface of cells. Several important human proteins affected include fibrin, albumin, casein, angiotensin II and bradykinin. Albumin is a blood protein that provide contributions to the maintenance of a healthy blood flow, while angiotensin II and bradykinin play a role in the pliability of blood vessels. All of these compounds are highly involved in the complex systems that are implicated in a healthy flow of blood. Bromelain is also occasionally used to alleviate some complications of cardiovascular disease. This is because Bromelain works like a blood thinner. Bromelain may also help with your bruises. Bruises are collections of blood under the skin that heal by breaking up and then being reabsorbed by skin tissues. Bromelain speeds this process up by thinning the collected blood, which in turn makes it easier for your body to reabsorb them. Due to its blood-thinning qualities, you should not take Bromelain if you are going to be taking prescription blood thinners. Why should I take Doctor’s Best 3000 GDU Bromelain? Doctor’s Best 3000 GDU Bromelain is a crude extract from the Ananas comosus (pineapple) plant that contains one of the most highly regarded and studied plant enzymes, bromelain. The use of bromelain has foundations in folk medicine, as Ananas comosus was used by the aboriginal inhabitants of Central and South America for various facets of health promotion. Bromelain is renowned for its protein digesting activity. The ability of the thiol-endopeptidase enzymes in bromelain to break down proteins leads to bromelain’s most noted health-promoting properties. The enzymatic activity of bromelain is measured by its ability to digest various substrates. GDU, or gelatin-digesting units, are a common measure of bromelain’s potency.
