How will High Potency Grapine help me? Nature’s Sunshine’s Grapine is an optimal blend of proanthocyanidins derived from grape seeds and maritime pine bark. Grape seed extract has a rich antioxidant content; one type of polyphenol called oligomeric proanthocyanidin (OPC) is present at higher concentrations than all the others. The maritime pine tree (Pinus pinaster), contains naturally occurring chemicals called proanthocyanidins. The maritime pine is native to the western Mediterranean. Grapine’s proanthocyanidins help protect cells from oxidative damage and are quickly absorbed into the body. Use this product when high levels of polyphenols are desired. What are polyphenols? Polyphenols are micronutrients with antioxidant activity, found most abundantly in whole foods such as fruits, vegetables, and cocoa. Proanthocyanidins (PAs) are a class of polyphenols, also known as condensed tannins, are very powerful antioxidants that remove harmful free radicals, activated oxygen molecules, from cells.