Glucosamine Sulfate helps joint health for joint lubrication, better joint movement and flexibility. Cartilage, composed of proteoglycans, is mainly located on bones, near the joints and consists primarily of collagen protein with side chains called chondroitin sulfate. MSM supplies bioavailable sulfur needed to support joint health, hair, skin, and nails. NutraKey Glucosamine Chondroitin MSM is ultra micronized for maximum bioavailability.