What is Doctor’s Best French Red Wine Grape Extract? Doctor’s Best French Red Wine Grape Extract supports healthy aging and maintains healthy cardiovascular function. It contains BioVin Advanced, a French Red Wine extract made from whole red wine grapes. BioVin Advanced contains 5% red wine trans-resveratrol and 30-35% red wine polyphenols, including anthocyanins and other flavonoids. Each capsule of French Red Wine Grape Extract provides the resveratrol equivalent of 3 glasses of red wine. How does it work? The whole grape constituents in BioVin Advanced enhance the body’s antioxidant defenses to counteract the effects of free radicals. Resveratrol is involved in activating the human enzyme SIRT1, which is involved in a variety of cellular processes, such as energy metabolism, fat mobilization, and insulin secretion Resveratrol and red wine polyphenols have been shown to support healthy cardiovascular function and promote healthy aging.