What Does DIM + CDG Do? DIM + CDG supports multiple detoxification pathways involved in healthy hormonal regulation. Calcium D-Glucarate (CDG) supports glucuronidation, which is an important pathway in detoxification. BioResponse DIM provides the cruciferous indole, Diindolylmethane (DIM), which is also involved in the liver’s natural detoxification process. DIM + CDG supports healthy estrogen and testosterone balance in both women and men.