What Does Bone-Up Three Per Day Do? Bone-Up provides StimuCal ossein MicroCrystalline HydroxyApatite (MCHA) (from free-range New Zealand calves), which includes the superior combination of the inorganic calcium lattice of MCHA within an organic protein milieu. StimuCal is rich in native type I collagen—the predominant protein found in bone—and has been clinically demonstrated not to disproportionately spike calcium blood levels as do other forms of calcium, such as the carbonate and citrate salt forms. StimuCal is combined with vitamin D3 and vitamin K2 (as MK-7 [menaquinone-7] from natural fermentation [a more bioavailable form of vitamin K]) to support the proper deposition of calcium into the bones, as well as assist in building up the bone matrix. Bone Up also supports cardiovascular and arterial health.