Promotes Bone Density Supports Cardiovascular Health Complete Multinutrient Bone-Health System. Published Clinical Trial With Bone-Up StimuCal MicroCrystalline HydroxyApatite Complex. Source of natural bone-growth factors. Often Imitated Bone Supplement. Bone-Up is always UP-FORMULATED to include the latest breakthroughs in bone health. Bone-Up provides StimuCal ossein MicroCrystalline HydroxyApatite (MCHA) (from free-range New Zealand calves), which includes the superior combination of the inorganic calcium lattice of MCHA within an organic protein milieu. StimuCal is rich in native type I collagen—the predominant protein found in bone—and has been clinically demonstrated not to disproportionately spike calcium blood levels as do other forms of calcium, such as the carbonate and citrate salt forms. StimuCal is combined with vitamin D3 and vitamin K2 (as MK-7 from natural fermentation [a more bioavailable form of vitamin K]) to support the proper deposition of calcium into the bone matrix, thereby maintaining skeletal integrity, as well as supporting cardiovascular and arterial health. Potassium citrate is a systemic alkalizer added for optimal osteo support.